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How to interpret the pattern of high citrate, low cis-aconitate, low glutamate, and high glutamine.

Anonymous attendee says, are there other known causes ??? aconitate, high citric acid, glutamate low, glutamine normal high besides oxidative stress, all nutrients test okay per the Cheat Sheet Okay, so these are, the aconitate and citric acid are markers on the citric acid cycle where we metabolize most of our energy

If citric acid is high and isocitric acid is low, this must be the Great Plains Test which doesn't have isocitrate, cis-aconitate seems to be the next best thing that's closely related That would indicate oxidative stress The glutamate is low, the glutamine is normal, I don't know, I don't think that's relevant to oxidative stress so I don't see any basis to think of anything other than oxidative stress for the citric acid cycle markers In terms of the glutamate being low, if your glutamate is low and your glutamine is on the high side then you probably, you have ammonia generation from somewhere that you're mopping up with glutamate That would be my guess, but that's another can of worms to open

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